Recent Publications — The Bell Labs, University of San Diego

Bell Lab Presentations with Published Abstracts for Collaborators

This is a password protected area- please contact Ellis Bell, jbell@sandiego.edu to register for a password.

Jessica Bell-20 Publications since 2010

“Length of course-based undergraduate research experiences (CURE) impacts student learning and attitudinal outcomes: A study of the Malate dehydrogenase CUREs Community (MCC)”, DeChenne-Peters SE, Rakus JF, Parente AD, Mans TL, Eddy R, Galport N, Courtney Koletar, Joseph J. Provost, J. Ellis Bell, & Jessica K. Bell (2023) . PLoS ONE 18(3): e0282170. https://doi.org/10.1371/journal.pone.0282170

"External Collaboration Results in Student Learning Gains and Positive STEM Attitudes in CUREs" Kevin P. Callahan, Celeste N. Peterson, Betsy M. Martinez-Vaz, Kathryn L. Huisinga, Nicole Galport, Courtney Koletar, Rebecca M. Eddy, Joseph J. Provost, Jessica K. Bell and Ellis Bell. CBE Life Sciences. in press, 2022

“Allosterism & Drug Discovery” by J.Ellis Bell & Jessica K Bell. Burger’s Medicinal Chemistry, Drug Discovery & Development, 8th Edition, Wiley, in press, 2020

“Skills and Foundational Concepts for Biochemistry Students” by Ellis Bell, Joseph Provost, and Jessica K. Bell, Biochemistry Education: From Theory to Practice, Chapter 4, ACS Publications, 2020

“Development and Use of CUREs in Biochemistry” by Joseph J. Provost, Jessica K. Bell, and John E. Bell, Biochemistry Education: From Theory to Practice, Chapter 7, ACS Publications, 2020

“Lab eNotebooks” by Keri Colabroy and Jessica K. Bell, Biochemistry Education: From Theory to Practice, Chapter 8, ACS Publications, 2020

“Predicting and validating a model of Suppressor of IKKepsilon through biophysical characterization” by Megan L. Machek, Halie A. Sonnenschein, Sasha-Kaye I. Graham, Flowreen Shikwana, Seung-Hwan L. Kim, Selena Garcia-Dubar, Ian D. Minzer, Ryan Wey & Jessica K. Bell. 2019, In Press in Protein Science

"Suppressor of IKKepsilon forms direct interactions with cytoskeletal proteins, tubulin and α-actinin, linking innate immunity to the cytoskeleton" by Halie A. Sonnenschein, Kenneth F. Lawrence, Karli A. Wittenberg, Frank A. Slykas, Emerald L. Dohleman, Jilan B. Knoublauch, Sean M. Fahey, Timothy M Marshall, Jr., James D. Marion and Jessica K. Bell, FEBS Open Bio. 2018 Jun 19;8(7):1064-1082

CUREs in biochemistry-where we are and where we should go.

Bell JK, Eckdahl TT, Hecht DA, Killion PJ, Latzer J, Mans TL, Provost JJ, Rakus JF, Siebrasse EA, Ellis Bell J. Biochem Mol Biol Educ. 2017 Jan 2;45(1):7-12. doi: 10.1002/bmb.20989. Epub 2016 Jun 30.

Cyclic-di-GMP binding induces structural rearrangements in the PlzA and PlzC proteins of the Lyme disease and relapsing fever spirochetes: a possible switch mechanism for c-di-GMP-mediated effector functions.

Mallory KL, Miller DP, Oliver LD Jr, Freedman JC, Kostick-Dunn JL, Carlyon JA, Marion JD, Bell JK, Marconi RT., Pathog Dis. 2016 Nov;74(8). pii: ftw105. Epub 2016 Oct 18.

Analysis of the complement sensitivity of oral treponemes and the potential influence of FH binding, FH cleavage and dentilisin activity on the pathogenesis of periodontal disease.

Miller DP, McDowell JV, Bell JK, Goetting-Minesky MP, Fenno JC, Marconi RT. Mol Oral Microbiol. 2014 Oct;29(5):194-207. doi: 10.1111/omi.12054. Epub 2014 Jun 3.

Mechanism of endogenous regulation of the type I interferon response by suppressor of IκB kinase epsilon (SIKE), a novel substrate of TANK-binding kinase 1 (TBK1).

Marion JD, Roberts CF, Call RJ, Forbes JL, Nelson KT, Bell JE, Bell JK. J Biol Chem. 2013 Jun 21;288(25):18612-23. doi: 10.1074/jbc.M112.440859. Epub 2013 May 6.

Sequence divergence in the Treponema denticola FhbB protein and its impact on factor H binding.

Miller DP, McDowell JV, Rhodes DV, Allard A, Caimano M, Bell JK, Marconi RT. Mol Oral Microbiol. 2013 Aug;28(4):316-30. doi: 10.1111/omi.12027. Epub 2013 Apr 22.

Homology model and targeted mutagenesis identify critical residues for arachidonic acid inhibition of Kv4 channels.

Heler R, Bell JK, Boland LM., Channels (Austin). 2013 Mar-Apr;7(2):74-84. doi: 10.4161/chan.23453. Epub 2013 Jan 18.

Lateral clustering of TLR3:dsRNA signaling units revealed by TLR3ecd:3Fabs quaternary structure.

Luo J, Obmolova G, Malia TJ, Wu SJ, Duffy KE, Marion JD, Bell JK, Ge P, Zhou ZH, Teplyakov A, Zhao Y, Lamb RJ, Jordan JL, San Mateo LR, Sweet RW, Gilliland GL., J Mol Biol. 2012 Aug 3;421(1):112-24. doi: 10.1016/j.jmb.2012.05.006. Epub 2012 May 9.

Innate immune agonist, dsRNA, induces apoptosis in ovarian cancer cells and enhances the potency of cytotoxic chemotherapeutics.

Van DN, Roberts CF, Marion JD, Lépine S, Harikumar KB, Schreiter J, Dumur CI, Fang X, Spiegel S, Bell JK. , FASEB J. 2012 Aug;26(8):3188-98. doi: 10.1096/fj.11-202333. Epub 2012 Apr 24.

Structure of factor H-binding protein B (FhbB) of the periopathogen, Treponema denticola: insights into progression of periodontal disease.

Miller DP, Bell JK, McDowell JV, Conrad DH, Burgner JW, Héroux A, Marconi RT., J Biol Chem. 2012 Apr 13;287(16):12715-22. doi: 10.1074/jbc.M112.339721. Epub 2012 Feb 24.

Crystallization of the factor H-binding protein, FhbB, from the periopathogen Treponema denticola.

Miller DP, McDowell JV, Bell JK, Marconi RT., Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jun 1;67(Pt 6):678-81. doi: 10.1107/S1744309111011298. Epub 2011 May 25.

The TOLL of inflammation in multiple myeloma.

Bell JK., Cancer Biol Ther. 2011 Jan 1;11(1):68-70. Epub 2011 Jan 1. No abstract available.

Measuring the effect of ligand binding on the interface stability of multimeric proteins using dynamic light scattering.

Marion JD, Van DN, Bell JE, Bell JK., Anal Biochem. 2010 Dec 15;407(2):278-80. doi: 10.1016/j.ab.2010.08.019. Epub 2010 Aug 21.

Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.

Yacoub A, Liu R, Park MA, Hamed HA, Dash R, Schramm DN, Sarkar D, Dimitriev IP, Bell JK, Grant S, Farrell NP, Curiel DT, Fisher PB, Dent P., Mol Pharmacol. 2010 Feb;77(2):298-310. doi: 10.1124/mol.109.061820. Epub 2009 Nov 12.

Joint Publications- 9 since 2010

“Allosterism & Drug Discovery” by J.Ellis Bell & Jessica K Bell. Burger’s Medicinal Chemistry, Drug Discovery & Development, 8th Edition, Wiley, in press, 2020

“Skills and Foundational Concepts for Biochemistry Students” by Ellis Bell, Joseph Provost, and Jessica K. Bell, Biochemistry Education: From Theory to Practice, Chapter 4, ACS Publications, 2020

“Development and Use of CUREs in Biochemistry” by Joseph J. Provost, Jessica K. Bell, and John E. Bell, Biochemistry Education: From Theory to Practice, Chapter 7, ACS Publications, 2020

CUREs in biochemistry-where we are and where we should go.

Bell JK, Eckdahl TT, Hecht DA, Killion PJ, Latzer J, Mans TL, Provost JJ, Rakus JF, Siebrasse EA, Ellis Bell J., Biochem Mol Biol Educ. 2017 Jan 2;45(1):7-12. doi: 10.1002/bmb.20989. Epub 2016 Jun 30.

Mechanism of endogenous regulation of the type I interferon response by suppressor of IκB kinase epsilon (SIKE), a novel substrate of TANK-binding kinase 1 (TBK1).

Marion JD, Roberts CF, Call RJ, Forbes JL, Nelson KT, Bell JE, Bell JK., J Biol Chem. 2013 Jun 21;288(25):18612-23. doi: 10.1074/jbc.M112.440859. Epub 2013 May 6.

Measuring the effect of ligand binding on the interface stability of multimeric proteins using dynamic light scattering.

Marion JD, Van DN, Bell JE, Bell JK., Anal Biochem. 2010 Dec 15;407(2):278-80. doi: 10.1016/j.ab.2010.08.019. Epub 2010 Aug 21.

Ellis Bell-17 since 2010

“Allosterism & Drug Discovery” by J.Ellis Bell & Jessica K Bell. Burger’s Medicinal Chemistry, Drug Discovery & Development, 8th Edition, Wiley, in press, 2020

“Teaching Virtual Protein-Centric CUREs and UREs Using Computational Tools”, Anthony Bell, Laura Christian, David Hecht, Kathryn Huisinga, John Rakus & Ellis Bell, BAMBED, in press, 2020

“Skills and Foundational Concepts for Biochemistry Students” by Ellis Bell, Joseph Provost, and Jessica K. Bell, Biochemistry Education: From Theory to Practice, Chapter 4, ACS Publications, 2020

“Development and Use of CUREs in Biochemistry” by Joseph J. Provost, Jessica K. Bell, and John E. Bell, Biochemistry Education: From Theory to Practice, Chapter 7, ACS Publications, 2020

CUREs in biochemistry-where we are and where we should go.

Mechanism of endogenous regulation of the type I interferon response by suppressor of IκB kinase epsilon (SIKE), a novel substrate of TANK-binding kinase 1 (TBK1).

Marion JD, Roberts CF, Call RJ, Forbes JL, Nelson KT, Bell JE, Bell JK., J Biol Chem. 2013 Jun 21;288(25):18612-23. doi: 10.1074/jbc.M112.440859. Epub 2013 May 6.

Measuring the effect of ligand binding on the interface stability of multimeric proteins using dynamic light scattering.

Marion JD, Van DN, Bell JE, Bell JK., Anal Biochem. 2010 Dec 15;407(2):278-80. doi: 10.1016/j.ab.2010.08.019. Epub 2010 Aug 21.

A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis.

Bailey J, Powell L, Sinanan L, Neal J, Li M, Smith T, Bell E., FEBS J. 2011 Sep;278(17):3140-51. doi: 10.1111/j.1742-4658.2011.08240.x. Epub 2011 Aug 11.

Ligand-induced changes in the conformational stability and flexibility of glutamate dehydrogenase and their role in catalysis and regulation.

Wacker SA*, Bradley MJ*, Marion J, Bell E., Protein Sci. 2010 Oct;19(10):1820-9

A national comparison of biochemistry and molecular biology capstone experiences.

Aguanno A, Mertz P, Martin D, Bell E., Biochem Mol Biol Educ. 2015 Jul-Aug;43(4):223-32. doi: 10.1002/bmb.20869. Epub 2015 Jul 14.

Introduction: promoting concept driven teaching strategies in biochemistry and molecular biology.

Mattos C, Johnson M, White H, Sears D, Bailey C, Bell E., Biochem Mol Biol Educ. 2013 Sep-Oct;41(5):287-8. doi: 10.1002/bmb.20726. No abstract available.

What skills should students of undergraduate biochemistry and molecular biology programs have upon graduation?

White HB, Benore MA, Sumter TF, Caldwell BD, Bell E., Biochem Mol Biol Educ. 2013 Sep-Oct;41(5):297-301. doi: 10.1002/bmb.20729. Epub 2013 Sep 10.

Essential concepts and underlying theories from physics, chemistry, and mathematics for "biochemistry and molecular biology" majors.

Wright A, Provost J, Roecklein-Canfield JA, Bell E., Biochem Mol Biol Educ. 2013 Sep-Oct;41(5):302-8. doi: 10.1002/bmb.20728. Epub 2013 Sep 10.

Foundational concepts and underlying theories for majors in "biochemistry and molecular biology".

Tansey JT, Baird T Jr, Cox MM, Fox KM, Knight J, Sears D, Bell E., Biochem Mol Biol Educ. 2013 Sep-Oct;41(5):289-96. doi: 10.1002/bmb.20727. Epub 2013 Sep 10.

Commentary: Biochemistry and molecular biology educators launch national network.

Bailey C, Bell E, Johnson M, Mattos C, Sears D, White HB., Biochem Mol Biol Educ. 2010 Jul;38(4):266-7. doi: 10.1002/bmb.20424. No abstract available.

Using research to teach an "introduction to biological thinking".

Bell E., Biochem Mol Biol Educ. 2011 Jan-Feb;39(1):10-6. doi: 10.1002/bmb.20441.